Towards stem cell replacement therapies for Parkinson's disease.

  title={Towards stem cell replacement therapies for Parkinson's disease.},
  author={Ernest Arenas},
  journal={Biochemical and biophysical research communications},
  volume={396 1},
Current therapeutic approaches for Parkinson's disease (PD) provide symptomatic relief but none of them change the course of disease. There is therefore a clear need for regenerative and cell replacement therapies (CRT). However, CRT faces several important challenges. First, the main symptoms of PD result from the loss of midbrain dopamine (DA) neurons, but other cell types are also affected. Second, transplantation of human ventral midbrain tissue from aborted fetuses has lead to proof of… CONTINUE READING


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