Towards personalized, tumour-specific, therapeutic vaccines for cancer

Abstract

Cancer vaccines, which are designed to amplify tumour-specific T cell responses through active immunization, have long been envisioned as a key tool of effective cancer immunotherapy. Despite a clear rationale for such vaccines, extensive past efforts were unsuccessful in mediating clinically relevant antitumour activity in humans. Recently, however, next… (More)
DOI: 10.1038/nri.2017.131

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