Towards chemical analysis of nanostructures in biofilms I: imaging of biological nanostructures.

@article{Schmid2008TowardsCA,
  title={Towards chemical analysis of nanostructures in biofilms I: imaging of biological nanostructures.},
  author={Thomas W Schmid and Johannes A Burkhard and Boon-Siang Yeo and Weihua Zhang and Renato Zenobi},
  journal={Analytical and bioanalytical chemistry},
  year={2008},
  volume={391 5},
  pages={1899-905}
}
Due to their direct influence on the stability of bacterial biofilms, a better insight into the nanoscopic spatial arrangement of the different extracellular polymeric substances (EPS), e.g., polysaccharides and proteins, is important for the improvement of biocides and for process optimization in wastewater treatment and biofiltration. Here, the first application of a combination of confocal laser-scanning microscopy (CLSM) and atomic force microscopy (AFM) to the investigation of river-water… CONTINUE READING
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