Towards axonal regeneration and neuroprotection in glaucoma: Rho kinase inhibitors as promising therapeutics

@article{Velde2015TowardsAR,
  title={Towards axonal regeneration and neuroprotection in glaucoma: Rho kinase inhibitors as promising therapeutics},
  author={Sarah Van de Velde and Lies De Groef and Ingeborg Stalmans and Lieve Moons and Inge Van Hove},
  journal={Progress in Neurobiology},
  year={2015},
  volume={131},
  pages={105-119}
}
Due to a prolonged life expectancy worldwide, the incidence of age-related neurodegenerative disorders such as glaucoma is increasing. Glaucoma is the second cause of blindness, resulting from a slow and progressive loss of retinal ganglion cells (RGCs) and their axons. Up to now, intraocular pressure (IOP) reduction is the only treatment modality by which ophthalmologists attempt to control disease progression. However, not all patients benefit from this therapy, and the pathophysiology of… CONTINUE READING

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