Towards an Understanding of the Herpes Simplex Virus Type 1 Latency-Reactivation Cycle

@inproceedings{Perng2010TowardsAU,
  title={Towards an Understanding of the Herpes Simplex Virus Type 1 Latency-Reactivation Cycle},
  author={Guey-chuen Perng and Clinton Jones},
  booktitle={Interdisciplinary perspectives on infectious diseases},
  year={2010}
}
Infection by herpes simplex virus type 1 (HSV-1) can cause clinical symptoms in the peripheral and central nervous system. Recurrent ocular shedding can lead to corneal scarring and vision loss making HSV-1 a leading cause of corneal blindness due to an infectious agent. The primary site of HSV-1 latency is sensory neurons within trigeminal ganglia. Periodically, reactivation from latency occurs resulting in virus transmission and recurrent disease. During latency, the latency-associated… CONTINUE READING
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