Towards a taxonomic coherence between average nucleotide identity and 16S rRNA gene sequence similarity for species demarcation of prokaryotes.

@article{Kim2014TowardsAT,
  title={Towards a taxonomic coherence between average nucleotide identity and 16S rRNA gene sequence similarity for species demarcation of prokaryotes.},
  author={Mincheol Kim and Hyun-seok Oh and Sang-Cheol Park and Jongsik Chun},
  journal={International journal of systematic and evolutionary microbiology},
  year={2014},
  volume={64 Pt 2},
  pages={346-51}
}
Among available genome relatedness indices, average nucleotide identity (ANI) is one of the most robust measurements of genomic relatedness between strains, and has great potential in the taxonomy of bacteria and archaea as a substitute for the labour-intensive DNA-DNA hybridization (DDH) technique. An ANI threshold range (95-96%) for species demarcation had previously been suggested based on comparative investigation between DDH and ANI values, albeit with rather limited datasets. Furthermore… CONTINUE READING
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