Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: a position paper of the Working Group 'Myocardial Function' of the ESC.

@article{Knoell2011TowardsAR,
  title={Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: a position paper of the Working Group 'Myocardial Function' of the ESC.},
  author={Ralph Knoell and Guido Iaccarino and Guido Tarone and Denise Hilfiker-Kleiner and Johann Bauersachs and Adelino F Leite-Moreira and Peter H. Sugden and Jean-Luc Balligand},
  journal={European journal of heart failure},
  year={2011},
  volume={13 8},
  pages={811-9}
}
Many primary or secondary diseases of the myocardium are accompanied with complex remodelling of the cardiac tissue that results in increased heart mass, often identified as cardiac 'hypertrophy'. Although there have been numerous attempts at defining such 'hypertrophy', the present paper delineates the reasons as to why current definitions of cardiac hypertrophy remain unsatisfying. Based on a brief review of the underlying pathophysiology and tissue and cellular events driving myocardial… CONTINUE READING
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