Towards a molecular characterisation of pathological pathways.


The dominant conceptual reductionism in drug discovery has resulted in many promising drug candidates to fail during the last clinical phases, mainly due to a lack of knowledge about the patho-physiological pathways they are acting on. Consequently, to increase the revenues of the drug discovery process, we need to improve our understanding of the molecular… (More)
DOI: 10.1016/j.febslet.2008.02.014


Cite this paper

@article{Pache2008TowardsAM, title={Towards a molecular characterisation of pathological pathways.}, author={Roland A. Pache and Andreas Zanzoni and Jordi Naval and Jos{\'e} M. Mas and Patrick Aloy}, journal={FEBS letters}, year={2008}, volume={582 8}, pages={1259-65} }