Towards a long-term model construction for the dynamic simulation of HIV infection.

@article{Hadjiandreou2007TowardsAL,
  title={Towards a long-term model construction for the dynamic simulation of HIV infection.},
  author={Marios M. Hadjiandreou and Ra{\'u}l Conejeros and Vassilis Vassiliadis},
  journal={Mathematical biosciences and engineering : MBE},
  year={2007},
  volume={4 3},
  pages={489-504}
}
This study involves the mathematical modelling of long-term HIV dynamics. The proposed model is able to predict the entire trajectory of the disease: initial viremia in the early weeks of the infection, latency, and progression to AIDS; a range spanning approximately ten years. The model outcomes were compared to clinical data and significant agreement was achieved. The formulated model considers all important population compartments including macrophages, latently-infected CD4+ T-cells, and… CONTINUE READING