Towards a cellular multi-parameter analysis platform: Fluorescence in situ hybridization (FISH) on microhole-array chips

  title={Towards a cellular multi-parameter analysis platform: Fluorescence in situ hybridization (FISH) on microhole-array chips},
  author={Christian M. Kurz and Stefan V. D. Moosdijk and Hagen Thielecke and Thomas Velten},
  journal={2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
  • Christian M. Kurz, S. V. D. Moosdijk, +1 author T. Velten
  • Published 1 December 2011
  • Materials Science, Medicine, Computer Science
  • 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Highly-sensitive analysis systems based on cellular multi-parameter are needed in the diagnostics. Therefore we improved our previously developed chip platform for another additional analysis method, the fluorescence in situ hybridization. Fluorescence in situ hybridization (FISH) is a technique used in the diagnostics to determine the localization and the presence or absence of specific DNA sequence. To improve this labor- and cost-intensive method, we reduced the assay consumption by a factor… Expand
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