Towards a ZP-based contraceptive for marsupials: comparative analysis and developmental expression of marsupial ZP genes.

@article{McCartney2007TowardsAZ,
  title={Towards a ZP-based contraceptive for marsupials: comparative analysis and developmental expression of marsupial ZP genes.},
  author={Carmen A McCartney and Merrilee S Harris and John Cameron Rodger and Karen E Mate},
  journal={Molecular reproduction and development},
  year={2007},
  volume={74 12},
  pages={1581-9}
}
Fertility control in the form of a zona pellucida (ZP)-based immunocontraceptive has shown potential as a humane form of control for overabundant marsupials including the brushtail possum and macropods. Further refinement and development of a ZP-based vaccine requires detailed knowledge of the protein structure and expression in order to ensure maximum efficacy and specificity. Sequencing and comparative analysis of the ZP3 protein from three marsupial orders in this study found a high overall… CONTINUE READING