Towards Real-Time Control of Gene Expression: Controlling the Hog Signaling Cascade

@article{Uhlendorf2011TowardsRC,
  title={Towards Real-Time Control of Gene Expression: Controlling the Hog Signaling Cascade},
  author={Jannis Uhlendorf and Samuele Bottani and François Fages and Pascal Hersen and Gr{\'e}gory Batt},
  journal={Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing},
  year={2011},
  pages={338-49}
}
To decipher the dynamical functioning of cellular processes, the method of choice is to observe the time response of cells subjected to well controlled perturbations in time and amplitude. Efficient methods, based on molecular biology, are available to monitor quantitatively and dynamically many cellular processes. In contrast, it is still a challenge to perturb cellular processes - such as gene expression - in a precise and controlled manner. Here, we propose a first step towards in vivo… CONTINUE READING
Highly Cited
This paper has 45 citations. REVIEW CITATIONS