Towards Optimal Thermal Distribution in Magnetic Hyperthermia

@inproceedings{Rytov2021TowardsOT,
  title={Towards Optimal Thermal Distribution in Magnetic Hyperthermia},
  author={Ruslan A Rytov and V.A. Bautin and Nikolai A. Usov},
  year={2021}
}
A linear combination of spherically symmetric heat sources is shown to provide optimal stationary thermal distribution in magnetic hyperthermia. Furthermore, such spatial location of heat sources produces suitable temperature distribution in biological medium even for assemblies of magnetic nanoparticles with a moderate value of specific absorption rate (SAR), of the order of 100 - 150 W/g. We also demonstrate the advantage of using assemblies of magnetic nanocapsules consisting of metallic… 

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References

SHOWING 1-10 OF 41 REFERENCES
Large specific absorption rates in the magnetic hyperthermia properties of metallic iron nanocubes
We report on the magnetic hyperthermia properties of chemically synthesized ferromagnetic 11 and 16 nm Fe(0) nanoparticles of cubic shape displaying the saturation magnetization of bulk iron. The
Optimal Size of Nanoparticles for Magnetic Hyperthermia: A Combined Theoretical and Experimental Study
Progress in the prediction and optimization of the heating of magnetic nanoparticles in an alternating magnetic field is highly desirable for their application in magnetic hyperthermia. Here, a model
Magnetic nanoparticle heating and heat transfer on a microscale: Basic principles, realities and physical limitations of hyperthermia for tumour therapy
  • S. Dutz, R. Hergt
  • Materials Science, Medicine
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • 2013
TLDR
Practical aspects, limitations, and the state of the art for the application of magnetic heating in magnetic particle hyperthermia as thermal treatment of small tumours are illuminated.
Effect of magnetic dipolar interactions on nanoparticle heating efficiency: Implications for cancer hyperthermia
TLDR
Analysis of ferromagnetic resonance data shows that high particle concentrations correlate with increasing chain length producing decreasing SLP, and a theoretical model describing dipole interactions valid for the linear response regime is proposed, predicting optimum particle sizes for hyperthermia to about 30% smaller than those previously predicted, depending on the nanoparticle parameters and chain size.
Fundamental solutions to the bioheat equation and their application to magnetic fluid hyperthermia
  • Mauricio A. Giordano, G. Gutiérrez, C. Rinaldi
  • Materials Science, Medicine
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • 2010
TLDR
The fundamental solutions of Pennes’ bioheat equation derived in rectangular, cylindrical, and spherical coordinates are addressed and an almost uniform temperature profile is obtained inside the tumour with little penetration of therapeutic temperatures to the outer region of healthy tissue.
A computational study of the bioheat transfer in magnetic hyperthermia cancer therapy
The temperature analysis in magnetic hyperthermia focuses on the main parameters that have a fundamental role in thermal damage of malignant tissue. This paper studies the influence of the parameters
Design Maps for the Hyperthermic Treatment of Tumors with Superparamagnetic Nanoparticles
TLDR
The hyperthermic performance of commercially available formulations of superparamagnetic iron oxide nanoparticles (SPIOs), with core diameter of 5, 7 and 14 nm, in terms of absolute temperature increase ΔT and specific absorption rate (SAR) is studied.
Optimal Parameters for Hyperthermia Treatment Using Biomineralized Magnetite Nanoparticles: Theoretical and Experimental Approach
We hereby present experimental and theoretical insights on the use of biomineralized magnetite nanoparticles, called magnetosomes, as heat nanoinductors in the magnetic hyperthermia technique. The
Transient solution to the bioheat equation and optimization for magnetic fluid hyperthermia treatment
  • H. Bagaria, D. Johnson
  • Materials Science, Medicine
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • 2005
TLDR
It was found that, for a fixed amount of magnetic particles, optimizing the magnetic particle distribution in the diseased tissue can significantly enhance the therapeutic temperature levels in the Diseased tissue while maintaining the same level of heating in the healthy tissue.
Magnetic particle hyperthermia--a promising tumour therapy?
TLDR
A critical review of the state of the art of magnetic particle hyperthermia (MPH) as a minimal invasive tumour therapy and elucidates possibilities, prospects, and challenges for establishment of MPH as a standard medical procedure.
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