Toward the discovery of new biomarkers of hepatocellular carcinoma by proteomics.

  title={Toward the discovery of new biomarkers of hepatocellular carcinoma by proteomics.},
  author={Enrique Santamar{\'i}a and Javier Mu{\~n}oz and Joaqu{\'i}n Fern{\'a}ndez-Irigoyen and Jes{\'u}s Prieto and Fernando Jos{\'e} Corrales},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  volume={27 2},
Primary liver cancer is the fifth most frequent neoplasm and the third most common cause of cancer-related death, with more than 500,000 new cases diagnosed yearly. The outcome for hepatocellular carcinoma (HCC) patients still remains dismal, partly because of our limited knowledge of its molecular pathogenesis and the difficulty in detecting the disease at its early stages. Therefore, studies aimed at the definition of the mechanisms associated with HCC progression and the identification of… CONTINUE READING
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