Toward the chemical ecology of medicinal plant use in chimpanzees: The case ofVernonia amygdalina, a plant used by wild chimpanzees possibly for parasite-related diseases

@article{Ohigashi1994TowardTC,
  title={Toward the chemical ecology of medicinal plant use in chimpanzees: The case ofVernonia amygdalina, a plant used by wild chimpanzees possibly for parasite-related diseases},
  author={Hajime Ohigashi and Michael Huffman and Daisuke Izutsu and Koichi Koshimizu and Masanori Kawanaka and Hiromu Sugiyama and Geoffrey C. Kirby and David Charles Warhurst and David Allen and Colin W. Wright and J. David Phillipson and Pierre Timon-David and Florence Delmas and Riad Elias and Guy Balansard},
  journal={Journal of Chemical Ecology},
  year={1994},
  volume={20},
  pages={541-553}
}
The bitter and related constituents have been isolated fromVernonia amygdalina (Compositae), a plant ingested by wild chimpanzees possibly suffering from parasite-related diseases in the Mahale Mountains National Park, Tanzania. Isolated from the plant were four known sesquiterpene lactones, seven new steroid glucosides, and two aglycones of the glucosides. The sesquiterpene lactones showed significant in vitro antischistosomal, plasmodicidal, and leishmanicidal activities. Antischistosomal… CONTINUE READING

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