Toward structure determination using membrane-protein nanocrystals and microcrystals.

Abstract

Membrane proteins are very important for all living cells, being involved in respiration, photosynthesis, cellular uptake and signal transduction, amongst other vital functions. However, less than 300 unique membrane protein structures have been determined to date, often due to difficulties associated with the growth of sufficiently large and well-ordered… (More)
DOI: 10.1016/j.ymeth.2011.12.006

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