Toward minimal bacterial cells: evolution vs. design.

@article{Moya2009TowardMB,
  title={Toward minimal bacterial cells: evolution vs. design.},
  author={Andr{\'e}s Moya and Rosario Gil and Amparo Latorre and Juli Peret{\'o} and Maria Pilar Garcill{\'a}n-Barcia and F Sebasti{\'a}n de la Cruz},
  journal={FEMS microbiology reviews},
  year={2009},
  volume={33 1},
  pages={225-35}
}
Recent technical and conceptual advances in the biological sciences opened the possibility of the construction of newly designed cells. In this paper we review the state of the art of cell engineering in the context of genome research, paying particular attention to what we can learn on naturally reduced genomes from either symbiotic or free living bacteria. Different minimal hypothetically viable cells can be defined on the basis of several computational and experimental approaches. Projects… CONTINUE READING

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