Toward local arterial input functions in dynamic contrast-enhanced MRI.

@article{Fluckiger2010TowardLA,
  title={Toward local arterial input functions in dynamic contrast-enhanced MRI.},
  author={Jacob U. Fluckiger and Matthias C. Schabel and Edward V. R. Dibella},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2010},
  volume={32 4},
  pages={924-34}
}
PURPOSE To present a method for estimating the local arterial input function (AIF) within a dynamic contrast-enhanced MRI scan, based on the alternating minimization with model (AMM) method. MATERIALS AND METHODS This method clusters a subset of data into representative curves, which are then input to the AMM algorithm to return a parameterized AIF and pharmacokinetic parameters. Computer simulations are used to investigate the accuracy with which the AMM is able to estimate the true AIF as a… CONTINUE READING