Toward creating cell membrane glyco-landscapes with glycan lipid constructs.

@article{Korchagina2012TowardCC,
  title={Toward creating cell membrane glyco-landscapes with glycan lipid constructs.},
  author={Elena Yu Korchagina and Alexander Tuzikov and Andrey A Formanovsky and Inna S Popova and Stephen Henry and Nicolai N Bovin},
  journal={Carbohydrate research},
  year={2012},
  volume={356},
  pages={238-46}
}
Synthetic glycolipid-like constructs dispersible in biological media and capable of incorporating into cell membranes have the ability to create novel artificial glyco-landscapes on living cells. Using a variety of different glycans ranging from disaccharides to polysaccharides, together with different lengths and high hydrophilicity spacers, we created a series of synthetic glycolipid-like constructs. Contacting these constructs with live cells gave modified cells with controlled glycan… CONTINUE READING