Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress.

@article{Evans2010TowardCI,
  title={Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress.},
  author={M. D. R. Evans and Ryszard Olinski and Steffen Loft and Marcus S Cooke},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2010},
  volume={24 4},
  pages={1249-60}
}
Of the DNA-derived biomarkers of oxidative stress, urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) is the most frequently measured. However, there is significant discrepancy between chromatographic and immunoassay approaches, and intratechnique agreement among all available chromatography-based assays and ELISAs is yet to be established. This is a significant obstacle to their use in large molecular epidemiological studies. To evaluate the accuracy of intra/intertechnique and… CONTINUE READING
43 Extracted Citations
46 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 43 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…