Toward an understanding of the molecular mechanisms of physiological cell death.

@article{Vaux1993TowardAU,
  title={Toward an understanding of the molecular mechanisms of physiological cell death.},
  author={David L. Vaux},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 3},
  pages={786-9}
}
  • David L. Vaux
  • Published 1993 in
    Proceedings of the National Academy of Sciences…
Cell death is a normal physiological process. Morphological studies have shown that cells that die by physiological mechanisms often undergo characteristic changes termed "apoptosis" or "programmed cell death." Recent work has begun to unravel the molecular mechanisms of these deaths and has shown that one of the primary cell-death pathways is conserved throughout much of evolution. In the nematode Caenorhabditis elegans programmed cell deaths are mediated by a mechanism controlled by the ced-9… CONTINUE READING

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