Toward a unified theory of childhood trauma and psychosis: A comprehensive review of epidemiological, clinical, neuropsychological and biological findings

@article{Misiak2017TowardAU,
  title={Toward a unified theory of childhood trauma and psychosis: A comprehensive review of epidemiological, clinical, neuropsychological and biological findings},
  author={Błażej Misiak and Maja Krefft and Tomasz Bielawski and Ahmed A. Moustafa and Maria M Sasiadek and Dorota Frydecka},
  journal={Neuroscience \& Biobehavioral Reviews},
  year={2017},
  volume={75},
  pages={393-406}
}

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References

SHOWING 1-10 OF 235 REFERENCES
A cognitive behavioural perspective on the relationship between childhood trauma and psychosis
  • A. Morrison
  • Psychology, Medicine
    Epidemiology and Psychiatric Sciences
  • 2009
TLDR
This editorial reviews the relationship between childhood trauma and the development of psychosis in adulthood and suggests that psychosis is a relatively understandable response to the experience of severe trauma, and recent cognitive models of psychosis can help to explain the underlying mechanisms in such a causal relationship.
Letter to the Editor: Childhood trauma as a risk factor for psychosis: the confounding role of cognitive functioning
TLDR
It is hypothesized that childhood trauma exerts neurobiological consequences that contribute to psychosis-associated cognitive impairment, and whether increased exposure to early traumas can explain the reduced cognitive performance associated with a vulnerability to experience psychotic symptoms, in nonclinical adults with and without psychotic experiences.
Impact of Different Childhood Adversities on 1-Year Outcomes of Psychotic Disorder in the Genetics and Psychosis Study
TLDR
It is suggested that there may be some specificity in the impact of childhood adversity on service use and social functioning among psychosis patients over the first year following presentation to mental health services.
Childhood trauma and psychosis - what is the evidence?
TLDR
Initial studies suggest that trauma-specific treatments are as beneficial for these patients as for other diagnostic groups, as well as biological mechanisms such as dysregulated cortisol and increased sensitivity to stress.
Childhood trauma and cognitive function in first-episode affective and non-affective psychosis
Childhood Adversities Increase the Risk of Psychosis: A Meta-analysis of Patient-Control, Prospective- and Cross-sectional Cohort Studies
TLDR
It is shown that childhood adversity is strongly associated with increased risk for psychosis and population attributable risk was 33% (16%–47%).
Childhood trauma and dissociation in first-episode psychosis, chronic schizophrenia and community controls
Sexual trauma increases the risk of developing psychosis in an ultra high-risk "prodromal" population.
TLDR
The findings suggest that sexual trauma may be an important contributing factor in development of psychosis for some individuals.
The impact of childhood adversity on the persistence of psychotic symptoms: a systematic review and meta-analysis
TLDR
It is tentatively suggested that reported exposure to adverse events in childhood is associated with persistence of PE and clinically relevant psychotic symptoms, which partially strengthens the case for addressing the consequences of early adversity in individuals presenting with psychotic phenomena to improve long-term outcomes.
Do specific early-life adversities lead to specific symptoms of psychosis? A study from the 2007 the Adult Psychiatric Morbidity Survey.
TLDR
The associations between sexual trauma, physical abuse, bullying, and being brought up in institutional or local authority care and reports of auditory hallucinations and paranoid beliefs in the 2007 Adult Psychiatric Morbidity Survey are examined.
...
...