Toward a theory of multilevel evolution: long-term information integration shapes the mutational landscape and enhances evolvability.

@article{Hogeweg2012TowardAT,
  title={Toward a theory of multilevel evolution: long-term information integration shapes the mutational landscape and enhances evolvability.},
  author={Paulien Hogeweg},
  journal={Advances in experimental medicine and biology},
  year={2012},
  volume={751},
  pages={
          195-224
        }
}
  • P. Hogeweg
  • Published 2012
  • Biology
  • Advances in experimental medicine and biology
Most of evolutionary theory has abstracted away from how information is coded in the genome and how this information is transformed into traits on which selection takes place. While in the earliest stages of biological evolution, in the RNA world, the mapping from the genotype into function was largely predefined by the physical-chemical properties of the evolving entities (RNA replicators, e.g. from sequence to folded structure and catalytic sites), in present-day organisms, the mapping itself… 
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