Toward a rational strategy for prostate cancer screening based on long-term risk of prostate cancer metastases and death: Data from a large, unscreened, population-based cohort followed for up to 30 years.

@article{Lilja2011TowardAR,
  title={Toward a rational strategy for prostate cancer screening based on long-term risk of prostate cancer metastases and death: Data from a large, unscreened, population-based cohort followed for up to 30 years.},
  author={Hans G Lilja and Caroline J. Savage and Axel Gerdtsson and Thomas Bjork and Jonas Manjer and Per Anders Nilsson and Anders Dahlin and Anders Bjartell and Peter T. Scardino and David Ulmert and Andrew J. Vickers},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2011},
  volume={29 15_suppl},
  pages={4512}
}
4512 Background: Prostate-specific antigen (PSA) testing remains controversial due to high number of men need to be screened to prevent one death. Current screening recommendations are based on few data. We analyzed PSA in archived blood plasma collected in 1974-92 as part of the Malmö Preventive Project. This is a large, representative cohort of Swedish men not subject to screening, chiefly accruing at age 44-50 (i.e. shortly before PSA is recommended to begin in US) and followed for up to 30… CONTINUE READING