Toward a multimodal neuroprotective treatment of stroke.

  title={Toward a multimodal neuroprotective treatment of stroke.},
  author={Andreas Rogalewski and Armin Schneider and E. Bernd Ringelstein and Wolf R{\"u}diger Sch{\"a}bitz},
  volume={37 4},
BACKGROUND AND PURPOSE Stroke remains a common medical problem with importance attributable to the demographic changes in industrialized societies. SUMMARY OF REVIEW After years of setbacks, acute stroke therapy has finally emerged, including thrombolysis with tissue plasminogen activator (t-PA). However, t-PA treatment is limited by a narrow time window and side effects, so that only 3% of all stroke patients receive thrombolysis. Unimodal targeting of key events in stroke pathophysiology… CONTINUE READING

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