Toward a digital gene response: RNA G-quadruplexes with fewer quartets fold with higher cooperativity.

Abstract

Changes in RNA conformation can alter gene expression. The guanine quadruplex sequence (GQS) is an RNA motif that folds in the presence of K(+) ions. Changes in the conformation of this motif could be especially important in regulating gene expression in plants because intracellular K(+) concentrations often increase during drought stress. Little is known… (More)
DOI: 10.1021/ja2096255

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