Toward a better raft model: modulated phases in the four-component bilayer, DSPC/DOPC/POPC/CHOL.

  title={Toward a better raft model: modulated phases in the four-component bilayer, DSPC/DOPC/POPC/CHOL.},
  author={Shih Lin Goh and Jonathan J Amazon and Gerald W. Feigenson},
  journal={Biophysical journal},
  volume={104 4},
The liquid-liquid (Ld + Lo) coexistence region within a distearoyl-phosphatidylcholine/dioleoyl-phosphatidylcholine/palmitoyl-oleoyl-phosphatidylcholine/cholesterol (DSPC/DOPC/POPC/CHOL) mixture displays a nanoscopic-to-macroscopic transition of phase domains as POPC is replaced by DOPC. Previously, we showed that the transition goes through a modulated phase regime during this replacement, in which patterned liquid phase morphologies are observed on giant unilamellar vesicles (GUVs). Here, we… CONTINUE READING
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