Toward a Detailed Description of the Thermally Induced Dynamics of the Core Promoter


Establishing the general and promoter-specific mechanistic features of gene transcription initiation requires improved understanding of the sequence-dependent structural/dynamic features of promoter DNA. Experimental data suggest that a spontaneous dsDNA strand separation at the transcriptional start site is likely to be a requirement for transcription… (More)
DOI: 10.1371/journal.pcbi.1000313


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