Toward Self-Organization and Complex Matter

  title={Toward Self-Organization and Complex Matter},
  author={Jean‐Marie Lehn},
  pages={2400 - 2403}
  • J. Lehn
  • Published 29 March 2002
  • Chemistry
  • Science
Beyond molecular chemistry based on the covalent bond, supramolecular chemistry aims at developing highly complex chemical systems from components interacting through noncovalent intermolecular forces. Over the past quarter century, supramolecular chemistry has grown into a major field and has fueled numerous developments at the interfaces with biology and physics. Some of the conceptual advances and future challenges are profiled here. 

Perspectives in Chemistry: From Supramolecular Chemistry to Constitutional Dynamic Chemistry towards Adaptive Chemistry

  • J. Lehn
  • Chemistry, Materials Science
  • 2007
Supramolecular chemistry is actively exploring systems undergoing self-organization, i.e. systems capable of spontaneously generating well-defined functional supramolecular architectures by

Dynamic MATERIALS: Towards Functional Adaptive Materials.

A Constitutional Dynamic Chemistry (CDC) on both the molecular and supramolecular levels is defined to allow a continuous modification in constitution by reorganization and exchange of building blocks.

From supramolecular chemistry towards constitutional dynamic chemistry and adaptive chemistry.

  • J. Lehn
  • Chemistry, Biology
    Chemical Society reviews
  • 2007
Supramolecular chemistry considers chemical objects and systems capable of responding to external solicitations by modification of their constitution through component exchange or reorganisation, and opens the way towards an adaptive and evolutive chemistry, a further step towards the chemistry of complex matter.

Supramolecular self-assembly codes for functional structures

This work discusses the development of chemical structure codes for supramolecular self-assembly objects with defined shapes and the resulting materials formed are promising for electronic functions and biological functions for regenerative medicine.

A supramolecular peptide polymer from hydrogen-bond and coordination-driven self-assembly

A terpyridine- and guanine-functionalized peptide was developed that could form different morphologies by self-assembly or coordination with Fe2+ in dimethyl sulfoxide. The self-assembly of the pep

Building co-crystals with molecular sense and supramolecular sensibility

Molecular recognition is typically associated with molecules in solution, but such events are also responsible for organizing molecules in the solid state. Translating principles of molecular

Facile synthesis and supramolecular chemistry of hydrogen bond/halogen bond-driven multi-tasking tectons.

A one-step procedure for the synthesis of tectons equipped with powerful hydrogen- and halogen-bond donors is presented and can be used as synthetic vectors without structural interference.

Phase separation of supramolecular and dynamic block copolymers

The growing synergy between supramolecular chemistry and polymer synthesis is driven by the realization that the dynamic nature of non-covalent interactions may bring new properties and material

Supramolecular chemistry: from molecular information towards self-organization and complex matter*

Molecular chemistry has developed a wide range of very powerful procedures for constructing ever more sophisticated molecules from atoms linked by covalent bonds. Beyond molecular chemistry lies

Non-equilibrium supramolecular polymerization

Going beyond equilibrium polymerization is an exciting new direction in the field of supramolecular chemistry and the preparation protocol and mechanistic insights allow to identify each one of them.



Self Assembly in Supramolecular Systems

Self-assembly: What Does it Mean? Intermolecular Interactions: The Glue of Supramolecular Chemistry Hydrogen-bonded and pi-Stacked Systems Rotaxanes Catenanes Metal-directed Synthesis - Rotaxanes,

Noncovalent Synthesis: Using Physical-Organic Chemistry To Make Aggregates

A molecule is usually understood to be a stable collection of atoms connected bv a continuous network of covalent bonds. The develipment of methods for constructing these networks has been a central

Comprehensive Supramolecular Chemistry

The aim of this book is to provide a history of Supramolecular Chemistry from its inception in the 1920s to the present day, with a focus on the period between 1950 and 1983.

Molecular self-assembly and nanochemistry: a chemical strategy for the synthesis of nanostructures.

The ability to prepare structures in the upper part of this range of sizes would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.

The crystal as a supramolecular entity

Dynamic Combinatorial Chemistry

By combining the advantages of combinatorial chemistry and supramolecular chemistry, dynamic combinatorial chemistry may become a powerful tool for drug discovery and materials science. In their

Supramolecular Liquid Crystals. Self-Assembly of a Trimeric Supramolecular Disk and Its Self-Organization into a Columnar Discotic Mesophase

6,7-Bis(alkyloxy)-2,3-dihydrophthalazine-1,4-diones self-assemble into lactim−lactam trimeric disks in solution as demonstrated by SEC and NMR. With suitable substituents, as in Phthal8, Phthal12,

Kinetic and Thermodynamic Control in Self-Assembly: Sequential Formation of Linear and Circular Helicates.

NMR and MS analysis as a function of time has shown that the self-assembly of a linear ligand with Fe2+ or Ni2+ , metal ions of octahedral coordination geometry, generates first a triple helicate and


For many decades, the construction of organic compounds in the laboratory has relied on the remarkable abilities of the 20th century ‘alchemists’ — namely, synthetic organic chemists — to make and

Perspectives in Supramolecular Chemistry—From Molecular Recognition towards Molecular Information Processing and Self‐Organization

The selective binding of a substrate by a molecular receptor to form a supramolecular species involves molecular recognition which rests on the molecular information stored in the interacting