With the growing reliance on net-centric warfare, understanding the effect of information operations (IO) on the overall mission becomes increasingly important. Our research seeks to develop metrics that provide insight into the mission-level effect of IO. We approach this goal by proposing comprehensive mission success metrics that provide a vehicle to analyze correlation with proposed information metrics. A quantitative analysis of relationships among information and mission metrics yields an ability to predict mission effect based on activity in the information space. This in turn may drive the derivation of operational requirements and the development of technology and strategy to better assure the mission. This paper presents initial progress toward identifying promising links between mission-level metrics and information metrics, as well as insights into potential applications, such as a combat system that adapts to information degradation.