Toward First Principle Medical Diagnostics: On the Importance of Disease-Disease and Sign-Sign Interactions


A fundamental problem in medicine and biology is to assign states, e.g., healthy or diseased, to cells, organs or individuals. State assignment or making a diagnosis is often a nontrivial and challenging process and, with the advent of omics technologies, the diagnostic challenge is becoming more and more serious. The challenge lies not only in the… (More)
DOI: 10.3389/fphy.2017.00032


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