Toward 21st century blood component replacement therapeutics: artificial oxygen carriers, platelet substitutes, recombinant clotting factors, and others.

@article{Kim2006Toward2C,
  title={Toward 21st century blood component replacement therapeutics: artificial oxygen carriers, platelet substitutes, recombinant clotting factors, and others.},
  author={Hae Won Kim and A. Gerson Greenburg},
  journal={Artificial cells, blood substitutes, and immobilization biotechnology},
  year={2006},
  volume={34 6},
  pages={537-50}
}
In this brief overview, recent progress and current status of blood substitute research and development is summarized. Current blood substitute development efforts are focused on red blood cell substitutes but substitutes for platelets and other blood components are also in progress. Red cell substitutes currently in various stages of development are semi-synthetic or synthetic oxygen carriers that include "stealth" or "masked" red cells, hemoglobin-based oxygen carriers and perfluorocarbon… CONTINUE READING