Tourette syndrome and other chronic tic disorders: an update on clinical management

  title={Tourette syndrome and other chronic tic disorders: an update on clinical management},
  author={Davide Martino and Tamara Pringsheim},
  journal={Expert Review of Neurotherapeutics},
  pages={125 - 137}
ABSTRACT Introduction: The management of Tourette syndrome (TS) and other chronic tic disorders occurs in multiple stages and begins with comprehensive assessment and complex psychoeducation. Behavioral and pharmacological interventions (second stage) are needed when tics cause physical or psychosocial impairment. Deep brain stimulation surgery or experimental therapies represent the third stage. Areas covered: Discussed are recent advances in assessment and therapy of chronic tic disorders… 
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This expert review evaluated the empirical support for behavioral and pharmacological interventions based on the results of randomized controlled trials (RCTs) for Chronic Tic Disorders and Tourette’s Disorder.
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Patients with tics that are refractory to conventional treatments may be candidates for deep brain stimulation, but further studies are needed to determine the optimal target selection.
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This literature review encompasses pharmacotherapies for tics, which include alpha agonists, antipsychotics, topiramate, botulinum toxin, and dopamine depleters.
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