Toughness and damage susceptibility in human cortical bone is proportional to mechanical inhomogeneity at the osteonal-level.


Limitations associated with current clinical fracture risk assessment tools highlight the need for increased understanding of the fracture mechanisms of the bone and, ideally, a means of assessing this in vivo. Being a multi-layered hierarchical structure, the overall properties of the bone are dictated by its structural and compositional properties over… (More)
DOI: 10.1016/j.bone.2015.03.020


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