Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels.

@article{Wu2017TouchTA,
  title={Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels.},
  author={Jason H. Y. Wu and Amanda H. Lewis and J{\"o}rg Grandl},
  journal={Trends in biochemical sciences},
  year={2017},
  volume={42 1},
  pages={57-71}
}
In 2010, two proteins, Piezo1 and Piezo2, were identified as the long-sought molecular carriers of an excitatory mechanically activated current found in many cells. This discovery has opened the floodgates for studying a vast number of mechanotransduction processes. Over the past 6 years, groundbreaking research has identified Piezos as ion channels that sense light touch, proprioception, and vascular blood flow, ruled out roles for Piezos in several other mechanotransduction processes, and… CONTINUE READING

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