Total synthesis of the sesquiterpene (+/-)-illudin C via an intramolecular nitrile oxide cycloaddition.

@article{Aungst2001TotalSO,
  title={Total synthesis of the sesquiterpene (+/-)-illudin C via an intramolecular nitrile oxide cycloaddition.},
  author={Ronald Alan Aungst and C. M. Chan and Raymond L. Funk},
  journal={Organic letters},
  year={2001},
  volume={3 16},
  pages={
          2611-3
        }
}
[reaction: see text] A convergent total synthesis of illudin C is described. The tricyclic ring system of the natural product was quickly assembled from cyclopropane and cyclopentene precursors via a novel oxime dianion coupling reaction and a subsequent intramolecular nitrile oxide-olefin cycloaddition. 
23 Citations
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