Total synthesis of quercetin 3-sophorotrioside.

  title={Total synthesis of quercetin 3-sophorotrioside.},
  author={Yuguo Du and Guohua Wei and Robert J. Linhardt},
  journal={The Journal of organic chemistry},
  volume={69 6},
5,7-dihydroxy-3-[beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl]-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one (quercetin 3-sophorotrioside), a flavonol triglycoside, isolated from Pisum sativum shoots and showing protective effects on liver injury induced by chemicals, was synthesized for the first time. The target compound was successfully synthesized in eight linear steps and in 39% overall yield through a combination of phase-transfer-catalyzed (PTC… CONTINUE READING