Total synthesis of eudesmane terpenes by site-selective C–H oxidations

@article{Chen2009TotalSO,
  title={Total synthesis of eudesmane terpenes by site-selective C–H oxidations},
  author={K. Chen and P. Baran},
  journal={Nature},
  year={2009},
  volume={459},
  pages={824-828}
}
From menthol to cholesterol to Taxol, terpenes are a ubiquitous group of molecules (over 55,000 members isolated so far) that have long provided humans with flavours, fragrances, hormones, medicines and even commercial products such as rubber. Although they possess a seemingly endless variety of architectural complexities, the biosynthesis of terpenes often occurs in a unified fashion as a ‘two-phase’ process. In the first phase (the cyclase phase), simple linear hydrocarbon phosphate building… Expand
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