Total synthesis of a functional designer eukaryotic chromosome (Science (2014) 344, 6179 (55-58))

  title={Total synthesis of a functional designer eukaryotic chromosome (Science (2014) 344, 6179 (55-58))},
  author={Narayana Annaluru and H{\'e}lo{\"i}se Muller and Leslie A. Mitchell and Sivaprakash Ramalingam and Giovanni Stracquadanio and Sarah M. Richardson and Jessica S. Dymond and Zheng Kuang and Lisa Scheifele and Eric M. Cooper and Yizhi Cai and Karen Zeller and Neta Agmon and Jeffrey S. Han and Michalis Hadjithomas and Jennifer Tullman and Katrina Caravelli and Kimberly M. Cirelli and Zheyuan Guo and Viktoriya London and Apurva Yeluru and Sindurathy Murugan and Karthikeyan Kandavelou and Nicolas Agier and Gilles Fischer and Kun Yang and J Andrew Martin and Murat Bilgel and Pavlo Bohutskyi and Kristin M. Boulier and Brian J. Capaldo and Joy Chang and Kristie Charoen and Woo Jin Choi and Peter Deng and James E. DiCarlo and Judy C. Doong and Jessilyn P. Dunn and Jason I. Feinberg and Christopher Fernandez and Charlotte E. Floria and David A. Gladowski and Pasha Hadidi and Isabel Emiko Ishizuka and Javaneh Jabbari and Calvin Y. L. Lau and Pablo A. Lee and Sean Li and Denise Lin and Matthias E. Linder and Jonathan Guyang Ling and Jaime Liu and Jonathan Liu and Mariya London and Henry Ma and Jessica Mao and Jessica E. McDade and Alexandra McMillan and Aaron M. Moore and Won Chan Oh and Yuxiao Ouyang and Ruchi Patel and Marina Paul and Laura C. Paulsen and Judy Qiu and Alex Rhee and Matthew G Rubashkin and Ina Y. Soh and Nathaniel E. Sotuyo and Venkatesh Srinivas and Allison Suarez and Andy Wong and Remus S Wong and Wei Rose Xie and Yijie Xu and Allen T. Yu and Romain Koszul and Joel S. Bader and Jef D. Boeke and Srinivasan Chandrasegaran},
A Role for the Budding Yeast Separase, Esp1, in Ty1 Element Retrotransposition
It is proposed that Esp1 serves two roles to mediate Ty1 transposition – one to remove cohesin and the second to target Ty1-IN to chromatin. Expand
Can life be engineered? Epistemological roots and blind spots of Synthetic Biology
Synthetic Biology is the latest attempt in experimental biology to reach the long lasting goal of mastering processes of life by engineering them. This emergent discipline results from the novelExpand