Total synthesis of (-)-conophylline and (-)-conophyllidine.

@article{Hanya2011TotalSO,
  title={Total synthesis of (-)-conophylline and (-)-conophyllidine.},
  author={Yuki Han-ya and Hidetoshi Tokuyama and Tohru Fukuyama},
  journal={Angewandte Chemie},
  year={2011},
  volume={50 21},
  pages={
          4884-7
        }
}
pound acts as a potent inhibitor of the ras function and, furthermore, has been found to induce beta-cell differentiation in rat pancreatic acinar carcinoma cells and in cultured fetal rat pancreatic tissue. Thus, this compound has the potential to be a lead compound in the development of novel drugs for cancer chemotherapy as well as for regeneration therapy used for the treatment of diabetes mellitus type 1. As a result of the important biological activity as well as the complex structure… 
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