Total nitric oxide production is low in patients with chronic renal disease.

@article{Schmidt2000TotalNO,
  title={Total nitric oxide production is low in patients with chronic renal disease.},
  author={Rebecca Schmidt and Christine Baylis},
  journal={Kidney international},
  year={2000},
  volume={58 3},
  pages={
          1261-6
        }
}
BACKGROUND A deficiency of the endogenous vasodilator nitric oxide (NO) has been implicated as a potential cause of hypertension in chronic renal disease (CRD) patients. This study was conducted to determine whether 24-hour NOX (NO2 and NO3) excretion (a qualitative index of total NO production) is reduced in patients with CRD. METHODS Measurements were made in 13 CRD patients and 9 normotensive healthy controls after 48 hours on a controlled low-NOX diet. Urine was collected over the second… CONTINUE READING
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