Total antioxidant status at high altitude in lowlanders and native highlanders: role of uric acid.

Abstract

Hypobaric hypoxia causes oxidative stress and the antioxidant system of the body plays a vital role in controlling it. Urate contributes up to two-thirds of the antioxidant capacity of human blood. The urate production is catalyzed by xanthine oxidase with a concomitant release of free radicals. This study was designed to appraise the role of urate as an… (More)
DOI: 10.1089/ham.2008.1082

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