Total Synthesis of (S)-(-)-Curvularin: A Ring-Closing-Metathesis-Based Constructionof the Macrocyclic Framework

@article{Mohapatra2008TotalSO,
  title={Total Synthesis of (S)-(-)-Curvularin: A Ring-Closing-Metathesis-Based Constructionof the Macrocyclic Framework},
  author={D. Mohapatra and H. Rahaman and R. Pal and M. K. Gurjar},
  journal={Synlett},
  year={2008},
  volume={2008},
  pages={1801-1804}
}
A convergent, flexible, and efficient approach to the synthesis of curvularin is described. Key step is the high-yielding macrocyclic ring formation by ring-closing metathesis (RCM) using the Grubbs second-generation catalyst. 
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