Total Syntheses of Juglorescein and Juglocombins A and B.

  title={Total Syntheses of Juglorescein and Juglocombins A and B.},
  author={Shogo Kamo and Kai Yoshioka and Kouji Kuramochi and Kazunori Tsubaki},
  journal={Angewandte Chemie},
  volume={55 35},
Total syntheses of juglorescein and juglocombins A and B are reported. The highly oxygenated 6/6/5/6/6-fused pentacyclic ring system of these natural products was constructed through a bioinspired dimerization of 1,4-naphthoquinone. Notably, five new stereogenic centers were constructed in a single step by the dimerization reaction. The epoxide intermediate obtained from the dimerization was successfully converted into juglocombins A and B through photoinduced reduction of the epoxide… 
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