Total C-21 steroidal glycosides, isolated from the root tuber of Cynanchum auriculatum Royle ex Wight, attenuate hydrogen peroxide-induced oxidative injury and inflammation in L02 cells

  title={Total C-21 steroidal glycosides, isolated from the root tuber of Cynanchum auriculatum Royle ex Wight, attenuate hydrogen peroxide-induced oxidative injury and inflammation in L02 cells},
  author={Zhen-hui Wu and Yingyu Wang and Xian-jie Meng and Xin-jie Wang and Zhenlin Li and Shihui Qian and Ying-jie Wei and Luan Shu and Yongfang Ding and Peijuan Wang and Yunru Peng},
  journal={International Journal of Molecular Medicine},
  pages={3157 - 3170}
Oxidative stress plays an important role in the pathology of liver disorders. Total C-21 steroidal glycosides (TCSGs), isolated from the root tuber of Cynanchum auriculatum Royle ex Wight, have been reported to exert numerous effects, including liver protective and antioxidant effects. In order to investigate the potential mechanisms underlying the protective effects of TCSGs on liver function, the present study used the human normal liver cell line, L02, to evaluate the effects of TCSGs on… 
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