Torrents of sequence

  title={Torrents of sequence},
  author={Nicole Rusk},
  journal={Nature Methods},
  • Nicole Rusk
  • Published 2011
  • Biology
  • Nature Methods
  • It is hard to overstate the positive changes that high-throughput sequencing has brought to biological research in the last few years. Each year developments with the potential to change the sequencing landscape emerge, and 2010 was no different. Ion Torrent launched in February 2010 with a sequencer based not on dye-labeled oligonucleotides and expensive optics but on ion detection (the machine has been casually referred to as ‘a pH meter that sequences’). The principle is straightforward: DNA… CONTINUE READING
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