Toroidal nucleoids in Escherichia coli exposed to chloramphenicol.

@article{Zimmerman2002ToroidalNI,
  title={Toroidal nucleoids in Escherichia coli exposed to chloramphenicol.},
  author={Steven B. Zimmerman},
  journal={Journal of structural biology},
  year={2002},
  volume={138 3},
  pages={199-206}
}
The DNA of growing cells of Escherichia coli occurs in one or a few lobular bodies known as nucleoids. Upon exposure to chloramphenicol, the nucleoids assume compact, rounded forms ("cm-nucleoids") that have been described as ring- or sphere-shaped. Multiple views of single cells or spheroplasts, however, support a different, curved toroid shape for cm-nucleoids. The multiple views were obtained either by DNA fluorescence imaging as the cells or spheroplasts reoriented in liquid medium or by… CONTINUE READING

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