Topological properties of two cubic phases of a phospholipid:cholesterol:diacylglycerol aqueous system and their possible implications in the phospholipase C-induced liposome fusion.

@article{Nieva1995TopologicalPO,
  title={Topological properties of two cubic phases of a phospholipid:cholesterol:diacylglycerol aqueous system and their possible implications in the phospholipase C-induced liposome fusion.},
  author={Jos{\'e} Luis Nieva and Alicia Alonso and Gorka Bas{\'a}{\~n}ez and F{\'e}lix M Go{\~n}i and A. van der Gulik and Rubicelia Vargas and Vittorio Luzzati},
  journal={FEBS letters},
  year={1995},
  volume={368 1},
  pages={143-7}
}
Water dispersions of phospholipid:cholesterol:diacylglycerol may, under certain conditions, originate either the lipid- and water-permeable Q224 cubic phase, or the lipid-permeable but water-impermeable Q227 cubic phase. These results are discussed within the framework of the phospholipase C-induced fusion of liposomes [Nieva et al. (1993) Biochemistry 32, 1054]. It is suggested that the cubic phases Q224 and Q227 represent two classes of lipid organization, one promoting, the other hindering… CONTINUE READING

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