Topological jamming of spontaneously knotted polyelectrolyte chains driven through a nanopore.

@article{Rosa2012TopologicalJO,
  title={Topological jamming of spontaneously knotted polyelectrolyte chains driven through a nanopore.},
  author={Angelo Rosa and Massimiliano Di Ventra and Cristian Micheletti},
  journal={Physical review letters},
  year={2012},
  volume={109 11},
  pages={
          118301
        }
}
The advent of solid state nanodevices allows for interrogating the physicochemical properties of a polyelectrolyte chain by electrophoretically driving it through a nanopore. Salient dynamical aspects of the translocation process have been recently characterized by theoretical and computational studies of model polymer chains free from self-entanglement. However, sufficiently long equilibrated chains are necessarily knotted. The impact of such topological "defects" on the translocation process… 

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