Topological features of a gene co-expression network predict patterns of natural diversity in environmental response

@article{DesMarais2017TopologicalFO,
  title={Topological features of a gene co-expression network predict patterns of natural diversity in environmental response},
  author={David L. Des Marais and Rafael F. Guerrero and Jesse R. Lasky and Samuel V. Scarpino},
  journal={Proceedings of the Royal Society B: Biological Sciences},
  year={2017},
  volume={284}
}
Molecular interactions affect the evolution of complex traits. For instance, adaptation may be constrained by pleiotropic or epistatic effects, both of which can be reflected in the structure of molecular interaction networks. To date, empirical studies investigating the role of molecular interactions in phenotypic evolution have been idiosyncratic, offering no clear patterns. Here, we investigated the network topology of genes putatively involved in local adaptation to two abiotic stressors… 

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